Research Interests: Mass Spectrometry, Organic Chemistry, Microchemical
techniques, Chromatography, GC-Infrared Spectrometry. Natural Products,
Chemical Communication and Defense in Arthropods, Chemical Ecology, “Chemical
Prospecting” by Pharmacological Screening of Tropical Rain Forest Natural
Products.
Research Interests: Mass Spectrometry, Fragmentation mechanisms,
Micro-scale Synthetic Organic Chemistry, Stable isotope labeled compounds.
Education:
2001 Doctorate Degree in Organic ChemistryCharles
University, Faculty of Science, Prague, Czech
Republic
Academy of Sciences of the Czech Republic,
Institute of Organic Chemistry and Biochemistry
1997 Master of Science Degree in Organic ChemistryCharles University,
Faculty of Science, Prague, Czech
Republic
1995 Bachelor of Science Degree in
ChemistryCharles University, Faculty of Science, Prague, Czech
Republic
Publications:
1. Ruzicka J., Streinz L., Saman D., Havlas Z., Wimmer Z., Zarevucka,M.,
Koutek B., Leseticky L., Chlorofluoroacetic Acid as a Highly Versatile
Derivatizing Agent: Assignment of Stereochemistry to Esters of Chiral
Alcohols, Collect. Czech. Chem. Commun. 2000, 65, 695
2. Ruzicka J., Koutek B., Streinz L., Saman D., Leseticky L., A new
access of b-methyl substituted secondary alcohols. Application
to the synthesis of 4-methylheptan-3-ol, Tetrahedron: Asymmetry 1999, 10,
3521
3. Ruzicka J., Streinz L., Wimmer Z., Rejzek M., Zarevucka M.,
Koutek M., Leseticky L., Chlorofluoroacetic Acid Derivatives
of Sterically
Hindered Chiral Alcohols, J. Chem. Res.,Synopses 1998,
830, Miniprint 1998, 3401
Research Interests: Mass Spectrometry, Microchemical techniques,
Chromatography, GC-Infrared Spectrometry. Natural Products, Chemical
Communication and Defense in Arthropods, Chemical Ecology.
Education:
Master of Science, Central China Normal University(CCNU) Bachelor
of Science, CCNU
Publications:
1. Wu Xiaogang, Lu Guanghan, Anodic voltammetric behavior of iodide
on a chitosan-modified glassy carbon electrode,Analytical Letters, 2001, 34,1205
- 1214
2. Lu Guanghan, Yao Xin, Wu Xiaogang, Determination of the total iron
by chitosan-modified glassy carbon electrode, Microchemical Journal,
2001, 69,81-87
3. Yao Xin, Lu Guanghan, Wu Xiaogang, Studies on Electrochemical
Behavior of Bromine at a Chitosan-modified Glassy Carbon Electrode Electroanalysis,
2001,13, 923-926
4. Lu Guanghan, Wu Xiaogang,
Studies on 1:12 phosphomolybdic heteropoly anion film modified
carbon paste
electrode. Talanta, 1999, 49, 511-515
5. Lu Guanghan*,
Wang Qionglin, Wu Xiaogang, etal. Polarographic determination
of trace fluoride in foods. Food Chemistry, 1999, 66,
519-523
6. Li Qiong, Lu Guanghan, Wu Heng, Xiaogang Wu. Determination
of trace tin in foods by single-sweep polarography. Food Chemistry,
1999, 64, 129-132
7. Wu Xiaogang, The electroanalytical
studies of 1:12 phosphomolybdic hetropoly acid film modified
electrode. J. Central China Normal Univ.(Nat. Sci), 1998,
22, 323-326
8. Wu Xiaogang, Application of polarographic
analysis in environmental samples. Environmental Science and Technology,
1998, No.2, 27-32.
Research Interests: Protein Chemistry, HPLC, Isolation of natural
Products
Education:
1974-79 University study: Charles University, Prague
1978-79 Department of Biochemistry, Charles University, Prague
1980-83 Ph.D. Institute of Organic Chemistry and Biochemistry,
Czechoslovak Academy of Sciences, Prague (Supervisor: Dr. Karel Jost)
Thesis: "Application of enzymes in peptide synthesis"
1983-1993 Research associate at the Institute of Organic Chemistry
and Biochemistry, Czechoslovak Academy of Sciences, Prague
1986 (1 month), 1987 (1 month) Visiting scholar: Institute
of Protein Research, Academy of Sciences of the USSR, Moscow Region,
USSR, and Laboratory of Peptide Synthesis, Institute of Cardiology,
Moscow, USSR
1989-90 (15 months) Postdoctoral study: Department of Biochemistry,
Indiana University Purdue University at Indianapolis, Indianapolis, USA
(Prof. Dr. Anna DePaoli Roach)
1992-93 (18 months) Alexander von Humboldt fellow (Leipzig
University, Leipzig, Germany.
(Prof. Dr. Hans-Dieter Jakubke)
1993-2000 Senior scientist and the leader of a small research
group at the Institute of Organic Chemistry and Biochemistry, Academy
of Sciences of the Czech Republic.
1993-1995 Joint work with Lonza AG, Switzerland
1997 (6 months) Follow-up-program of the Alexander von Humbold Foundation.
Institute für Enzymtechnologie, Forschungszentrum Jülich.
1998 (5 months), 1999 (4 months) Scholarships from German Scientific
Society (Deutsche Forschungsgemeinschaft), Leipzig University
Project leader: Dr. Frank Bordusa
2000 (3 months) Scholarship from Max-Planck-Society, Max-Planck
Research Unit, Enzymology of Protein Folding, Halle/Saale, Germany
2001-2003 (two years) Visiting scientist at the Department
of Chemistry and Chemical biology, Cornell University, Ithaca, NY,
USA (Prof. Harold A. Scheraga)
Publications:
Interaction of trypsin with immobilized
p-aminobenzamidine derivatives studied by means of affinity electrophoresis.
Cerovsky V., Ticha M., Turkova J., Labsky J. J. Chromatogr. 1980,
194, 175-181.
Studies on lectins. XLIX. The use of glycosyl
derivatives of Dextran T-500 for affinity electrophoresis of lectins.
Cerovsky V, Ticha M., Horejsi V., Kocourek J. Biochem. Biophys.
Methods 1980, 3, 163-172.
Papain-catalyzed synthesis of phenylhydrazides
of N-acylamino acids. Cerovsky V., Jost K. Collect. Czech. Chem.
Commun. 1984, 49, 2557-2561.
Enzymatic resolution of g-carboxy-DL-glutamic
acid. Cerovsky V., Jost K. Collect. Czech. Chem. Commun. 1984, 49,
2562-2565.
Enzymatically catalyzed synthesis of dipeptides
of g-carboxy-L-glutamic acid from benzyloxycarbonyl-g-carboxy-DL-glutamic
acid.Cerovsky V., Jost K. Collect. Czech. Chem. Commun. 1985, 50,
878-884.
Applicability of glutaminyl-tRNA cyclotransferase
in the peptide synthesis. Cerovsky V., Jost K. Collect. Czech. Chem.
Commun. 1985, 50, 2310-2318.
Enzymatically catalyzed synthesis of oxytocin
fragments 1-6 and 7-9. Cerovsky V., Jost K. Collect. Czech. Chem.
Commun. 1985, 50, 2775-2782. Synthesis of pressinoic acid by enzymatically
catalyzed formation of peptide bonds.Cerovsky V. Collect. Czech.
Chem. Commun. 1986, 51, 1352-1360.
Enzymatically catalyzed synthesis of dipeptides containing O4-sulfotyrosine
and O4-phosphotyrosine. Cerovsky V., Jost K. Collect.
Czech. Chem. Commun. 1987, 52, 1079-1086.
Papain-catalyzed synthesis of 2-naphtylamides of N-acylamino acids
and dipeptides.Cerovsky V., Saks T., Jost K. Collect. Czech. Chem.
Commun. 1987, 52, 2309-2316.
Synthesis of the carboxy-terminal octapeptide of cholecystokinin (CCK-8)
based on incorporation of O4-sulfotyrosine by enzymatically
catalyzed formation of peptide bonds. Cerovsky V., Hlavacek J., Slaninova
J., Jost K. Collect. Czech. Chem. Commun. 1988, 53, 1086-1093.
Enzymes in preparative organic synthesis: The problem of increasing
the yield of product. Semenov A.N., Cerovsky V., Titov M.I., Martinek
K. Collect. Czech. Chem. Commun. 1988, 53, 2963-2985.
Free chymotrypsin-catalyzed synthesis of peptide bond in aliphatic
alcohols with low water content. Cerovsky V., Martinek K. Collect.
Czech. Chem. Commun. 1989, 54, 266-276.
Peptide synthesis catalyzed by native
proteinase K in water-miscible organic solvents with low water content.
Cerovsky V., Martinek K. Collect. Czech. Chem. Commun. 1989, 54,
2027-2041.
Papain-catalyzed fragment synthesis of protected cholecystokinin derivatives.
Cerovsky V., Pirkova J., Majer P., Slaninova J, Hlavacek J. Collect.
Czech. Chem. Commun. 1990, 55, 1873-1882.
Free trypsin-catalyzed peptide synthesis in acetonitrile with low
water content. Cerovsky V. Biotechnol. Lett. 1990, 12, 899-904.
V8 proteinase-catalyzed peptide synthesis
in hydrophilic organic solvents with low water content. Cerovsky V. Tetrahedron
Lett. 1991, 32, 3421-3424.
Serine proteinase-catalyzed incorporation of D-amino acids into model
peptides in acetonitrile with low water content. Cerovsky V. Biomed.
Biochim. Acta 1991, 50, 44-49.
Protease-catalysed peptide synthesis in
solvent-free system. Cerovsky V. Biotechnol. Tech. 1992, 6, 155-160.
S`-Subsite mapping of polyethylene glycol-modified a-chymotrypsin
and a-chymotrypsin: a comparative study. Cerovsky V., Ullmann D., Jakubke
H.-D. Biochim. Biophys. Acta1994, 1204, 91-96.
Acyl transfer reactions catalyzed by native and modified a-chymotrypsin
in acetonitrile with low water content. Cerovsky V., Jakubke H.-D. Enzyme.
Microb. Technol. 1994, 16, 596-601.
Enzymatic approach to the synthesis of
taurine-containing peptides. Cerovsky V., Jakubke H.-D. Int. J.
Peptide Protein Res. 1994, 44, 466-471.
Peptide synthesis catalyzed by crosslinked
a-chymotrypsin in water/dimethylformamide system. Cerovsky V., Jakubke
H.-D. Biocatalysis 1994, 11, 233-240.
Serine/threonine protein phosphatases in the control of cell function.
DePaoli-Roach A., Park I.-K., Cerovsky V., Csortos S., Durbin S.D.,
Kuntz M.J., Sitikov A., Tang P.M., Verin A., Zolnierowicz S. Adv.
Enzyme Regul. 1994, 34, 199-224.
Nucleophile specificity of subtilisin
in an organic solvent with low water content. Investigation via acyl
transfer reactions. Cerovsky V., Jakubke H.-D. Biotechnol. Bioeng.
1996, 49, 553-558.
Protease-catalyzed synthesis of Leu-enkephalin in solvent free system.
Klein J. U., Cerovsky V. Int. J. Peptide Protein Res. 1996,
47, 348-352.
Enzymatic semisynthesis of dicarba-analogs
of calcitonin. Cerovsky V., Wunsch E., Brass J. Eur. J. Biochem.
1997, 247, 231-237.
Resolution of DL-2-aminosuberic acid via protease-catalyzed ester
hydrolysis. Rivard M., Malon P., Cerovsky V. Amino Acids 15, 1998,
389-392.
Peptides of 2-Aminosuberic Acid I. New intermediates for synthetic
studies. Wunsch E., Stocker H., Malon P., Gut V., Cerovsky V., Zertova
M., Laffan D.D. Amino Acids 2000, 18, 219-227.
Protease-catalyzed fragment condensation via substrate mimetic strategy:
a useful combination of solid-phase peptide synthesis with enzymatic
methods. Cerovsky V., Bordusa F. J. Peptide Res. 2000, 55, 325-329.
The applicability of subtilisin Carlsberg in peptide synthesis. Klein
J.-U., Prykhodzka A., Cerovsky V. J. Peptide Sci. 2000, 6, 541-549.
Semisynthesis of Ht 31(493-515): Involvement of PKA-anchoring proteins
in the regulation of the cAMP-dependent chloride current in heart cells.
Cerovsky V., Kockskaemper J., Glitsch H.G., Bordusa F. ChemBioChem2000,
1, 126-129.
Studies on the peptide amidase-catalyzed peptide amidation in organic
media with respect to its substrate specificity. Cerovsky V., Kula
M.-R.Biotechnol. Appl. Biochem. 2001, 33, 183-187
A convenient incorporation of conformationally constrained 5,5-dimethylproline
into the ribonuclease A 89-124 sequence by condensation of synthetic
peptide fragments. Cerovsky V., Welker E., Scheraga H.A. J. Peptide
Res. 2003, 61, 140-151
DoctoralThesis: “Southeast Asian Ant-Gardens: Diversity,
ecology, ecological significance and evolution of mutualistic ant-epiphyte
associations”
J. W. Goethe-University, Frankfurt, Germany. Oct.
1994 May
1998 “Diplom-Biologin” (comparable to Master of Science) in
Biological
Science. Thesis: “Ant gardens on giant bamboo (Gigantochloa
scortechinii, Poaceae) in West-Malaysia”
J. W. Goethe-University, Frankfurt, Germany. Oct.
1992 July 1994
“Vordiplom” (comparable to bachelor’s degree) in Zoology, Botany,
Chemistry and Physics.
Publications:
1. Kaufmann, E., A. Weissflog, R. Hashim, and U. Maschwitz, 2001.
Ant gardens on the giant bamboo Gigantochloa scortechinii (Poaceae)
in West-Malaysia. Insectes soc. 48: 125-133.
2. Malsch, A.K.F., E. Kaufmann, H.P. Heckroth, D.J. Williams, M. Maryati,
and U. Maschwitz, 2001. First report on root mealy bug (Homoptera:
Pseudococcidae) manipulation and sociobiology of Pseudolasius spp.
(Hymenoptera: Formicidae). Insectes soc. 48: 333-341.
3. Buschinger, A., U. Maschwitz and E. Kaufmann, 2002. Kein Kühlschrank?
No problem! Wie Crematogaster-Ameisen in den Feuchttropen das
Problem der Vorratshaltung lösen. Ameisenschutz aktuell 16: 1-5.
4. Kaufmann, E., A.K.F. Malsch, M. Erle and U. Maschwitz, in press.
Compound nesting of Strumigenys sp. (Myrmicinae) and Diacamma sp.
(Ponerinae), and other nesting symbioses of myrmicine and ponerine
ants in Southeast Asia. Insectes soc.
5. Kaufmann, E., A.K.F. Malsch, D.J. Williams and U. Maschwitz, in
press. Pseudolasius spp. and their trophobionts Codispersal
by colony-budding. Sociobiology
6. Kaufmann, E. and U. Maschwitz, 2002. The ‘ant epiphyte puzzle’ of
tropical Asian rain forests. In: XIV International Congress of IUSSI,
The Golden Jubilee Proceedings. Hokkaido University Press, Sapporo, Japan.
p. 3
7. Hashim, R., S.H. Yek, E. Kaufmann, T. Akino, J. Billen and F. Ito
(2002): Mimicry in an arboreal ant in Southeast Asia: Camponotus sp.,
a possible batesian mimic of Crematogaster inflata. In: XIV
International Congress of IUSSI, The Golden Jubilee Proceedings.
Hokkaido University Press, Sapporo, Japan.
p. 196
Kaufmann, E. and U. Maschwitz, submitted. Gardener ants and their
tree gardens: How to understand the ant-epiphyte puzzle of Asian tropical
rain forests. Behav. Ecol. Sociobiol.
Maschwitz, U., C. Go, E. Kaufmann and A. Buschinger, submitted. A
unique strategy of host colony exploitation in a parasitic ant: Workers
of Polyrhachis lama rear the brood of their colony in neighboring
host nests. Naturwissenschaften
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