|
| |
All Graduate courses are 3 credits except where noted.
See the registrar's web site for the current
course offerings. Select "Course Schedules" from the menu.
|
|
600-999 |
|
500-Level Courses
Ch 500 Physical Chemistry
Review
Review of undergraduate physical chemistry
by means of problem solving; atomic spectra; structure of atoms
and molecules; thermodynamics; changes of state; solutions;
chemical equilibrium; kinetic theory of gases; chemical kinetics
and electrochemistry. This course may not be counted toward the
master’s degree and is not open to undergraduate
students.
Ch 520 Advanced Physical
Chemistry
The elements of quantum mechanics are
developed and applied to chemical systems. Valence bond theory
and molecular orbital theory of small molecules; introduction to
group theory for molecular symmetry; fundamental aspects of
chemical bonding and molecular spectra.
Ch 540-541 Advanced Organic
Laboratory I-II*
Your needs and interests will be
considered in the assignment of typical advanced preparations,
small research problems and special operations.
Prerequisites:
one year of organic laboratory. Laboratory Fee: $60. Fall and
spring semesters.
Ch 561 Instrumental Methods of
Analysis
Primarily a laboratory course, with some
lecture presenting the principles and applications of
contemporary instrumental analytical methods, with a focus on
spectroscopy and separations. Laboratory practice explores
ultraviolet, visible and infrared spectrophotometry; atomic
absorption spectroscopy; nuclear magnetic resonance
spectrometry; gas-liquid and high-performance liquid
chromatography and mass spectrometry. These instrumental
techniques are utilized for quantitative and qualitative
analyses of organic, inorganic, biological and environmental
samples. Laboratory fee: $60.
Ch 580 Biochemistry I - Cellular
Metabolism and Regulation
Discussions include
metabolic pathways in biosynthesis and catabolism of
biomolecules, including carbohydrates, proteins, lipids and
nucleic acids. The hormonal regulation of metabolism as well as
vitamin metabolism is presented.
Prerequisites:
Ch 242 or equivalent.
Ch 582 Biophysical
Chemistry
The relationship of the chemical and
physical structure of biological macromolecules to their
biological functions as derived from osmotic pressure,
viscosity, light and X-ray scatting, diffusion,
ultracentrifugation and electrophoresis. The course is
subdivided into: 1) properties, functions and interrelations of
biological macromolecules, e.g., polysaccharides, proteins and
nucleic acids; 2) correlation of physical properties of
macromolecules in solution; 3) conformational properties of
proteins and nucleic acids and 4) aspects of metal ions in
biological systems.
Prerequisites:
Ch 421 or equivalent.
Ch 583 Physiology
Fundamentals of control processes governing physiological
systems analyzed at the cellular and molecular level. Biological
signal transduction and negative feedback control of metabolic
processes. Examples from sensory, nervous, cardiovascular and
endocrine systems. Deviations that give rise to abnormal states;
their detection, the theory behind the imaging and diagnostic
techniques such as MRI, PET, SPECT; the design and development
of therapeutic drugs. The principles, uses and applications of
biomaterials and tissue engineering techniques; problems
associated with biocompatibility. Students (or groups of
students) are expected to write and present a term
project.
Prerequisites:
Ch
382 or equivalent.
Courses Numbered 600 and Above
Ch 610 Advanced Inorganic and
Bioinorganic Chemistry
A systematic treatment of
the bonding and reactivity of inorganic substances; molecular
shape and electron charge distribution of main-group and
coordination compounds, including valence- bond theory and a
group theoretical approach to molecular orbital theory;
organometallic chemistry; the solid state; and the role of
inorganic compounds in biological processes and the
environment.
Ch 620 Chemical Thermodynamics and
Kinetics
Applications of the laws of thermodynamics
to solutions, electrolytes and polyelectrolytes, binding and
biological systems; statistical thermodynamics is developed and
applied to spectroscopy and transition state theory; chemical
kinetics of simple and complex reactions, enzyme and
heterogeneous catalysis and theories of reaction rates.
Ch 621 Quantum
Chemistry*
Theorems and postulates of quantum
mechanics; operator relationships; solutions of the Schrödinger
equation for model systems; variation and perturbation methods;
pure spin states; Hartree-Fock self-consistent field theory;
applications to many-electron atoms and molecules.
Prerequisites:
Ch 520 or equivalent.
Ch 622 Molecular
Spectroscopy*
Theoretical foundations of
spectroscopic methods and their application to the study of
molecular structure and properties. Theory of the absorption and
emission of radiation; line spectra of complex atoms; group
theory and rotational, vibrational, and electronic spectroscopy
of diatomic and polyatomic molecules.
Ch 623 Chemical
Kinetics*
A detailed discussion of the kinetics and
mechanism of complex reactions in the gaseous and liquid
phases. Topics include stationary and nonstationary conditions;
chain reactions; photo and radiation-induced reactions; and
reaction rate theories.
Ch 624 Statistical
Mechanics*
Classical and quantum mechanical
preliminaries; derivation of the laws of thermodynamics;
applications to monoatomic and polyatomic gases and to gaseous
mixtures; systems of dependent particles with applications to
the crystalline solid, the imperfect gas and the cooperative
phenomena; electric and magnetic fields; degenerate
gases.
Prerequisites:
Ch 620 or
equivalent.
Ch 640-641 Advanced Organic and
Heterocyclic Chemistry I-II
An advanced course in
the chemistry of carbon compounds, with special reference to
polyfunctional compounds, heterocycles, techniques of literature
survey, stereochemical concepts, physical tools for organic
chemists. Fall and spring semester.
Ch 642 Synthetic Organic
Chemistry
A survey of important synthetic methods
with emphasis on stereochemistry and reaction
mechanism.
Prerequisites:
Ch 640.
Ch 645 Chemistry of Heterocyclic
Compounds*
A survey of the more important classes
of heterocyclic compounds, their physical and chemical
properties, and methods of synthesis.
Prerequisites:
Undergraduate Organic Chemistry.
Ch 646 Chemistry of Natural
Products
Structure, synthesis and biogenesis of
antibiotics, alkaloids, hormones and other natural
products.
Prerequisites:
Undergraduate Organic Chemistry.
Ch 647 Chemistry and Pharmacology of
Drugs
Discussion at the molecular level of drug
receptor interaction, influence of stereochemistry and
physiochemical properties on drug action, pharmacological
effects of structural features, mechanism of drug action,
metabolic rate of drugs in animals and man, drug design. The
application of newer physical tools and recent advances in
methods for pharmacological studies will be
emphasized.
Prerequisites:
Undergraduate Organic Chemistry.
Ch 650 Spectra and Structure
Determination
An intensive course on the
interpretation of spectroscopic data; emphasis is on the use of
modern spectroscopic techniques, such as NMR (13C, D, 15N, H),
mass (including CI), laser-Raman, ESCA, ORD, CD, IR, UV for
structure elucidation. Special attention is given to the
application of computer technology in spectral work. A course
designed for practicing chemists in analytical, organic,
physical and biomedical areas. Extensive problem solving. No
laboratory.
Ch 660 Advanced Instrumental
Analysis
Advanced treatment of the theory and
practice of spectrometric methods (mass spectrometry, nuclear
magnetic resonance, etc.) and electroanalytical methods with
emphasis on Fourier Transform techniques (FTIR, FTNMR, etc.) and
hyphenated methods (gc-ms, etc.), the instrument-sample
interaction and signal sampling. A survey of computational
methods such as factor analysis and other chemometric methods is
also included.
Prerequisites:
Undergraduate Instrumental Analysis
with laboratory, or Ch 561.
Ch 661 Advanced Instrumental
Analysis Laboratory*
Your needs and interests are
considered in the assignment of work on one or more of the
following: NMR spectrometry, mass spectrometry, electrochemical
methods, infrared, ultraviolet and visible
spectrophotometry. Laboratory Fee: $60.
Ch 662 Separation Methods in
Analytical and Organic Chemistry
An advanced course
applying principles and theory to problems in chemical
analysis. Theory of separations, including distillation,
chromatography and ultracentrifugation; heterogeneity and
surface effects; sampling and its problems.
Ch 663 Design of Chemical
Instrumentation*
A practical treatment of the
mechanical, electronic and optical devices used in the
construction of instruments for research and chemical analysis
and control; motors, light sources and detectors,
servomechanisms, electronic components and test equipment,
vacuum and pressure measuring devices, and overall design
concepts are among the topics treated. Laboratory fee: $60.
Ch 664 Computer Methods in
Chemistry
Discusses computational chemistry topics,
including energy minimization, molecular dynamics, solvation
mechanics and electronic structure calculations. Applications
in drug design and receptors will be discussed.
Prerequisites:
Ch 321 or equivalent.
Ch 665 Chemometrics*
Application of chemometric techniques to problems in analytical,
physical and organic chemistry, with emphasis on spectroscopic
measurements. Includes optimization, analysis of variance,
pattern recognition, factor analysis, experimental design,
etc.
Ch 666 Modern Mass Spectrometry
(3-4-4)
A comprehensive hands-on course covering
both fundamentals and modern aspects of mass spectrometry with
emphasis on biological and biochemical applications. Topics
include: contemporary methods of gas phase ion formation
[electron ionization (EI), chemical ionization (CI), inductively
coupled plasma (ICP), fast atom bombardment (FAB), plasma
desorption (PD), electrospray (ESI), atmospheric pressure
chemical ionization (APCI), matrix assisted laser desorption
ionization (MALDI), detection (electron and photomultipliers,
array detectors) and mass analysis [magnetic deflection,
quadrupole, ion trap, time of flight (TOF), Fourier-transform
(FTMS)]. Detailed interpretation of organic mass spectra for
structural information with special emphasis on
even-electron-ion fragmentation. Qualitative and quantitative
applications in environmental, biological, pharmacological,
forensic, geochemical sciences.
Ch 668 Computational
Biology
Topics at the interface of biology and
computer technology will be discussed, including molecular
sequence analysis, phylogeny generation, biomolecular structure
simulation and modeling of site-directed
mutagenesis.
Prerequisites:
Ch 321, Ch 580 or equivalent.
Ch 670 Synthetic Polymer
Chemistry
Mechanisms and kinetics of organic and
inorganic polymerization reactions; condensation, free radical
and ionic addition, stereoregular polymerizations;
copolymerizations; the nature of chemical bonds and the
resulting physical properties of high polymers.
Ch 671 Physical Chemistry of
Polymers
Physio-chemical aspects of polymers,
molecular weight distributions, solution characterization and
theories, polymer chain configuration, thermodynamics of polymer
solutions, the amorphous state, the crystalline state.
Ch 672 Macromolecules in Modern
Technology
The course covers recent advances in
macromolecular science, including polyelectrolytes and
water-soluble polymers, synthetic and biological macromolecules
at surfaces, self-assembly of synthetic and biological
macromolecules, and polymers for biomedical applications.
Ch 673 Special Topics in Polymer
Chemistry*
Recent developments in polymer science
will be discussed, e.g., physical measurements, polymer
characterization, polymerization kinetics, morphology. Topics
will vary from year to year and specialists will
participate.
Ch 674 Polymer
Functionality
Topics at the interface of polymer
chemistry and the uses of polymers, focusing on areas where
polymers have made a particularly strong contribution, such as
in biomedical engineering and pharmaceutical
engineering. Synthesis and properties of biopolymers; polymers
whose properties change with the environment ("smart
polymers"); functional applications in tissue and cell
engineering; biosensors and drug delivery.
Prerequisites:
Undergraduate Organic Chemistry.
Ch 678 Experimental
Microbiology
Discussions in medical, industrial and
environmental microbiology will include bacteriology, virology,
mycology, parasitology and infectious diseases. Includes
experimental laboratory instruction. Laboratory fee:
$60.
Prerequisites:
Ch
382 or equivalent.
Ch 681 Biochemistry II -
Biomolecular Structure and Function
Discusses the
physical and structural chemistry of proteins and nucleotides,
as well as the functional role these molecules play in
biochemistry. Extensive use of known X-ray structural
information will be used to visualize the three- dimensional
structure of these biomolecules. This structural information
will be used to relate the molecules to known functional
information.
Prerequisites:
Ch 242 or equivalent.
Ch 682 Biochemical Laboratory
Techniques
Students will work actively in small
collaborative groups to solve a unique research project that
encompasses the purification, analysis of purity, kinetics and
structure-function analysis of a novel recombinant protein.
Techniques in protein purification, gel electrophoresis, peptide
digest separation, ligand binding, steady-state and stopped-flow
kinetics, and molecular simulation will be
explored.
Prerequisites:
admission into the graduate Chemical
Biology program. Laboratory fee: $60.
Ch 684 Molecular Biology Laboratory
Techniques
This laboratory course introduces
essential techniques in molecular biology and genetic
engineering in a project format. The course includes aseptic
technique and the handling of microbes; isolation and
purification of nucleic acids; construction, selection and
analysis of recombinant DNA molecules; restriction mapping;
immobilization and hybridization of nucleic acids; and labeling
methods of nucleic acid probes. Laboratory fee:
$60.
Prerequisites:
Ch
484 or equivalent.
Ch 685 Medicinal
Chemistry
A few topics of timely interest will be
treated in depth; recent chemical developments will be surveyed
in fields such as antibiotics, cancer chemotherapy, CNS agents,
chemical control of fertility, steroids and prostaglandins in
therapy, etc.
Prerequisites:
Ch 242 or equivalent.
Ch 686 Immunology
The
cells and molecules of the immune system and their interaction
and regulation; the cellular and genetic components of the
immune response, the biochemistry of antigens and antibodies,
the generation of antibody diversity, cytokines,
hypersensitivities and immunodeficiencies (i.e. AIDS);
transplants and tumors. Use of antibodies in currently emerging
immunodiagnostic techniques such as ELISA, disposable kits,
molecular targets, development of vaccines utilizing molecular
biological techniques such as recombinant and subunit vaccines.
Students (or groups of students) are expected to write and
present a term project.
Prerequisites:
Ch 381 or equivalent.
Ch 687 Molecular
Genetics
This course is a modern approach to the
study of heredity through molecular biology. Primary emphasis is
on nucleic acids, the molecular biology of gene expression,
molecular recognition and signal transduction, and bacterial and
viral molecular biology. The course will also discuss
recombinant DNA technology and its impact on science and
medicine.
Prerequisites:
Ch
484 or equivalent.
Ch 688 Methods in Chemical
Biology
A discussion of the theories underlying
various techniques of molecular biology which are used in the
biotechnology industry. Topics include all recombinant DNA
techniques; DNA isolation and analysis; library construction and
screening; cloning; DNA sequencing; hybridization and other
detection methods; RNA isolation and analysis; protein isolation
and analysis (immunoassay, ELISA, etc.); transgenic and ES cell
methods; electrophoresis (agarose, acrylamide, two dimensional
and SDS-PAGE); column chromatography; and basic cell culture
including transfection and expression systems.
Prerequisites:
Undergraduate biology, especially cell biology (Ch 381 or equivalent).
Ch 689 Cell Biology Laboratory
Techniques
Laboratory practice in modern biological
research will be explored. Techniques involving gene and protein
cellular probes, ELISA, mammalian cell culturing, cell cycle
determination, differential centrifugation, electron microscopy,
and fluorescent cellular markets will be
addressed.
Prerequisites:
admission into the graduate Chemical
Biology program and Ch 381 or equivalent. Laboratory fee:
$60.
Ch 700 Seminar in
Chemistry
Lectures by department faculty, guest
speakers and doctoral students on recent research. Enrollment
during the entire period of study is required of all doctoral
students. .5 credit, pass/fail. Must be taken every
semester.
Ch 720-721 Selected Topics in
Chemical Physics I-II*
Topics of current interest
selected by you are to be investigated from an advanced point of
view.
Ch 722 Selected Topics in Physical
Chemistry*
Topics selected to coincide with
research interests current in the department.
Ch 740 Selected Topics in Organic
Chemistry*
Selected topics of current interest in
the field of organic chemistry will be treated from an advanced
point of view; recent developments will be surveyed in fields
such as reaction mechanisms, physical methods in organic
chemistry, natural products chemistry, biogenesis, etc.
Ch 760 Chemoinformatics
This advanced course in computational chemistry builds on the
methods developed in Ch 664. Students will analyze and design
combinatorial libraries, develop SAR models and generate
calculated molecular properties. The hands-on course will use
both PC and Silicon Graphics computers. Software such as that
from Oxford Molecular, Tripos and Oracle will be used, as will
MSI software, such as INSIGHT/DISCOVER, Catalyst and Cerius
2.
Prerequisites:
Ch 664 or equivalent.
Ch 780-781 Selected Topics in
Biochemistry I-II*
Topics of current interest in
biochemical research are discussed, such as: enzyme chemistry,
biochemical genetics and development, cellular control
mechanism, biochemistry of cell membranes, bioenergetics and
microbiology.
Ch 782 Selected Topics in Bioorganic
Chemistry*
Topics of timely interest will be
treated in an interdisciplinary fashion; recent developments
will be surveyed in fields such as biosynthesis, radioactive and
stable isotope techniques, genesis of life chemicals, nucleic
acids and replication, genetic defects and metabolic errors.
Ch 800 Special Research Problems in
Chemistry*
One to six credits. Limit of six credits
for the degree of Master of Science.
Ch 801 Special Problems in
Chemistry*
One to six credits. Limit of six credits
for the degree of Doctor of Philosophy.
Ch 900 Thesis in
Chemistry*
For the degree of Master of Science,
five to ten credits with departmental approval.
Ch 960 Research in
Chemistry*
Original experimental or theoretical
research that may serve as the basis for the dissertation
required for the degree of Doctor of Philosophy. The work will
be carried out under the guidance of a faculty member. Hours and
credits to be arranged.
*by request
|
|
|
Updated Sat, 18-Aug-2007 at 15:45:06
|
Stevens Institute of Technology •
Hoboken, NJ • (201) 216-5000
|
|
